Imaging NMR and Graphene Oxide

Marcello ALECCI, Università degli Studi dell'Aquila

Magnetic resonance imaging (MRI) is a non invasive technique used to visualize anatomical structures in biomedical research and clinical medicine. The use of complexes of paramagnetic metal ions such as gadolinium (Gd3+), manganese (Mn2+), or iron (Fe2+) as MRI contrast agents (CAs), capable of changing the intrinsic relaxation times of in vivo water protons, has enabled improvements in diagnosis. However, better contrast and safety issues call for a novel class of CA. Recently the use of graphene-oxide based CA has been proposed as a new tool for MRI biomedical applications. In this talk we will review the current literature on CAs and present preliminary imaging results obtained in our lab by means of a 2.35T MRI scanner and graphene-oxide CA in water solutions.

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